four voltage-gated skeletal muscle ion channels
Spectrum of altered muscle excitability: The nondystrophic myotonias and familial periodic paralyses lie along a continuum of

Spectrum of altered muscle excitability: The nondystrophic myotonias and familial periodic paralyses lie along a continuum of muscle defects ranging from myotonia only to a combination of myotonia and periodic paralysis to periodic paralysis associated with sever multi-system involvement. All are caused by defects in the coding regions of voltage-gated ion channel genes (Stephen C. Cannon, 2002).