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Magnesium is an important ICF cation that contributes to many enzymatic and metabolic processes including protein synthesis. Magnesium modifies nerve impulse transmission and skeletal muscle response. Out of balance magnesium concentrations dramatically affect neuromuscular processes.
Hypomagnesemia is known to cause hyperirritability, tetany, leg and foot cramps, confusion, delusions, hallucinations, seizures, arrhythmias, and vasomotor changes.
Hypermagnesemia is known to cause diminished reflexes, muscle weakness, flaccid paralysis, drowsiness, flushing, lethargy, confusion, and diminished senses, bradycardia, weak pulse, hypotension, heart block, and cardiac arrest.
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